Saturday's game between the New York Yankees (36-17) and the San Diego Padres (27-27) at PETCO Park has a good chance to be a tight matchup, as our computer prediction projects a final score of 5-4, with the Yankees securing the victory. First pitch is at 9:40 PM ET on May 25.

The probable starters are Dylan Cease (5-3) for the Padres and Marcus Stroman (3-2) for the Yankees.

Watch MLB, other live sports and more on Fubo! Use our link to sign up for a free trial.

Padres vs. Yankees Game Info & Odds

Place your bets on any MLB matchup at BetMGM, and sign up with our link for a first-time deposit bonus!

Padres vs. Yankees Score Prediction

  • Our prediction for this matchup is Yankees 5, Padres 4.

Total Prediction for Padres vs. Yankees

  • Total Prediction: Over 7.5 runs

Padres Performance Insights

  • The Padres have played as the favorite in six of their past 10 games and won two of those contests.
  • In its last 10 games with a total, San Diego and its opponents have combined to hit the over eight times.
  • This season, the Padres have been favored 27 times and won 14, or 51.9%, of those games.
  • San Diego is 14-13 this season when entering a game favored by -115 or more on the moneyline.
  • The Padres have a 53.5% chance to win this game based on the implied probability of the moneyline.
  • San Diego has scored the eighth-most runs in the majors this season with 242.
  • The Padres have the 14th-ranked team ERA across all league pitching staffs (4.00).

Yankees Performance Insights

  • The Yankees have been an underdog just two times in their last 10 contests and won both matchups.
  • In its last 10 games with an over/under, New York and its opponents have combined to eclipse the total five times.
  • The Yankees have been chosen as underdogs in 13 games this year and have walked away with the win nine times (69.2%) in those games.
  • This season, New York has come away with a win eight times in 10 chances when named as an underdog of at least -105 or worse on the moneyline.
  • Oddsmakers have implied with the moneyline set for this matchup that the Yankees have a 51.2% chance of pulling out a win.
  • New York scores the third-most runs in baseball (260 total, 4.9 per game).
  • Yankees pitchers have a combined ERA of 2.81 ERA this year, first-best in baseball.

Put your picks to the test and bet with BetMGM!

Padres Schedule

Date Opponent Score Pitching Matchup
May 20 @ Braves L 3-0 Randy Vasquez vs Chris Sale
May 21 @ Reds L 2-0 Joe Musgrove vs Andrew Abbott
May 22 @ Reds W 7-3 Michael King vs Nick Martínez
May 23 @ Reds W 6-4 Matt Waldron vs Frankie Montás
May 24 Yankees L 8-0 Yu Darvish vs Carlos Rodón
May 25 Yankees - Dylan Cease vs Marcus Stroman
May 26 Yankees - Joe Musgrove vs Clarke Schmidt
May 27 Marlins - Michael King vs Trevor Rogers
May 28 Marlins - Matt Waldron vs Jesús Luzardo
May 29 Marlins - Yu Darvish vs Braxton Garrett
May 31 @ Royals - TBA vs TBA

Yankees Schedule

Date Opponent Score Pitching Matchup
May 20 Mariners L 5-4 Marcus Stroman vs Logan Gilbert
May 21 Mariners L 6-3 Clarke Schmidt vs Bryan Woo
May 22 Mariners W 7-3 Nestor Cortes Jr. vs Bryce Miller
May 23 Mariners W 5-0 Luis Gil vs Luis Castillo
May 24 @ Padres W 8-0 Carlos Rodón vs Yu Darvish
May 25 @ Padres - Marcus Stroman vs Dylan Cease
May 26 @ Padres - Clarke Schmidt vs Joe Musgrove
May 28 @ Angels - Nestor Cortes Jr. vs Griffin Canning
May 29 @ Angels - Luis Gil vs Tyler Anderson
May 30 @ Angels - Carlos Rodón vs Patrick Sandoval
May 31 @ Giants - TBA vs TBA

Rep your team with officially licensed MLB gear! Head to Fanatics to find jerseys, shirts, and much more.

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.

Upcoming Local Events

More local events

dataskrive is a Tribune-Review freelancer. You can contact dataskrive at info@triblive.com.