Christina Applegate has reportedly been hospitalized in Los Angeles since late March, amid the Emmy winner’s enduring battle with multiple sclerosis.
The 54-year-old “Dead to Me” star’s representative would not confirm the information given to TMZ by sources with direct knowledge, who claimed her lengthy hospitalization but could not detail the circumstances surrounding it.
“I have no comment on whether she is in the hospital or what her medical treatments are,” Applegate’s rep said in a statement to the Daily News. “She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.”
The “Married… with Children” alum was diagnosed in 2021 with MS, which affects communication between the brain and body, and damages nerve fibers. Symptoms can include difficulty with coordination and walking, partial or complete loss of vision, often in one eye at a time, slurred speech, mood changes, vertigo, and more.
In 2024, Applegate shared on the “MeSSy” podcast she hosts with “Sopranos” alum Jamie-Lynn Sigler, who also battles the autoimmune disease, that she does not “enjoy living” anymore and suffers now from “a real, f—k-it-all depression.”
“It’s kind of scaring me too a little bit because it feels really fatalistic,” said Applegate at the time.
She revealed in early 2025 that symptoms from MS had sent her to the hospital “upwards of 30 times” over three years. This past summer, she was also hospitalized with a double kidney infection.
Just weeks after the March 3 release of her memoir, “You With the Sad Eyes,” Applegate told NPR’s “Wild Card with Rachel Martin” that she had already purchased her burial plot as she feels death “looming” and thinks about it “every day.”