Wednesday's game between the Chicago Cubs (56-60) and the Minnesota Twins (63-49) at Wrigley Field is expected to be a close matchup, as our computer prediction projects a final score of 5-4, with the Cubs coming out on top. First pitch is at 2:20 PM ET on August 7.

The Twins will give the nod to Joe Ryan (7-7) against the Cubs and Javier Assad (5-3).

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Twins vs. Cubs Game Info & Odds

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Twins vs. Cubs Score Prediction

  • Our pick for this contest is Cubs 5, Twins 4.

Total Prediction for Twins vs. Cubs

  • Total Prediction: Over 6 runs

Discover More About This Game

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  • Tickets for Twins vs. Cubs
  • Twins Performance Insights

    • In seven games as the favorite over the last 10 matchups, the Twins have a record of 6-1.
    • Minnesota and its opponents have combined to hit the over six times in its last 10 games with a total.
    • The Twins have been favorites in 72 games this season and won 45 (62.5%) of those contests.
    • Minnesota has entered 72 games this season favored by -115 or more and is 45-27 in those contests.
    • The Twins have a 53.5% chance to win this game based on the implied probability of the moneyline.
    • Minnesota is among the highest-scoring teams in the majors, ranking sixth with 550 total runs this season.
    • The Twins have the 20th-ranked team ERA among all MLB pitching staffs (4.15).

    Cubs Performance Insights

    • In five games as the underdog over the last 10 matchups, the Cubs have posted a mark of 4-1.
    • In its previous 10 games with a total, Chicago and its opponents have combined to exceed the over/under on six occasions.
    • The Cubs have been underdogs in 64 games this season and have come away with the win 32 times (50%) in those contests.
    • Chicago has a mark of 25-28 in contests where sportsbooks favor it by -105 or worse on the moneyline.
    • The moneyline set for this matchup implies the Cubs have a 51.2% chance of coming away with a victory in the contest.
    • Chicago scores the 17th-most runs in baseball (485 total, 4.2 per game).
    • The Cubs have the seventh-best ERA (3.76) in the majors this season.

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    Twins Schedule

    Date Opponent Score Pitching Matchup
    August 2 White Sox W 10-2 Joe Ryan vs Davis Martin
    August 3 White Sox W 6-2 Bailey Ober vs Garrett Crochet
    August 4 White Sox W 13-7 Simeon Woods Richardson vs Chris Flexen
    August 5 @ Cubs W 3-0 David Festa vs Kyle Hendricks
    August 6 @ Cubs L 7-3 Pablo Lopez vs Shota Imanaga
    August 7 @ Cubs - Joe Ryan vs Javier Assad
    August 9 Guardians - Bailey Ober vs Gavin Williams
    August 9 Guardians - TBA vs TBA
    August 10 Guardians - Simeon Woods Richardson vs Gavin Williams
    August 11 Guardians - David Festa vs TBA
    August 12 Royals - Pablo Lopez vs Brady Singer

    Cubs Schedule

    Date Opponent Score Pitching Matchup
    August 2 Cardinals W 6-3 Javier Assad vs Erick Fedde
    August 3 Cardinals L 5-4 Jameson Taillon vs Kyle Gibson
    August 4 Cardinals W 6-2 Justin Steele vs Miles Mikolas
    August 5 Twins L 3-0 Kyle Hendricks vs David Festa
    August 6 Twins W 7-3 Shota Imanaga vs Pablo Lopez
    August 7 Twins - Javier Assad vs Joe Ryan
    August 9 @ White Sox - Jameson Taillon vs Garrett Crochet
    August 10 @ White Sox - Justin Steele vs Chris Flexen
    August 12 @ Guardians - Kyle Hendricks vs Ben Lively
    August 13 @ Guardians - Shota Imanaga vs TBA
    August 14 @ Guardians - TBA vs TBA

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    dataskrive is a Tribune-Review freelancer. You can contact dataskrive at info@triblive.com.