Wednesday's game features the Houston Astros (27-34) and the St. Louis Cardinals (28-30) facing off at Minute Maid Park in what is expected to be a competitive matchup, with a projected 4-3 win for the Astros according to our computer prediction. First pitch is at 2:10 PM ET on June 5.

The Astros will give the ball to Ronel Blanco (5-1, 2.44 ERA), who is eyeing win No. 6 on the season, and the Cardinals will turn to Miles Mikolas (3-6, 5.54 ERA).

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Astros vs. Cardinals Game Info & Odds

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Astros vs. Cardinals Score Prediction

  • Our prediction for this contest is Astros 4, Cardinals 3.

Total Prediction for Astros vs. Cardinals

  • Total Prediction: Under 9 runs

Astros Performance Insights

  • The Astros have played as the favorite in seven of their past 10 games and won three of those contests.
  • In its last 10 games with a total, Houston and its opponents have combined to hit the over just once.
  • This season, the Astros have been favored 46 times and won 21, or 45.7%, of those games.
  • Houston has entered 18 games this season favored by -159 or more and is 12-6 in those contests.
  • The oddsmakers' moneyline implies a 61.4% chance of a victory for the Astros.
  • Houston is among the highest-scoring teams in the majors, ranking 10th with 267 total runs this season.
  • The Astros' 4.27 team ERA ranks 21st among all league pitching staffs.

Cardinals Performance Insights

  • The Cardinals have played as the underdog in eight of their past 10 games and have gone 4-4 in those contests.
  • In its last 10 games with an over/under, St. Louis and its opponents have combined to eclipse the total two times.
  • The Cardinals have been victorious in 13, or 43.3%, of the 30 contests they have been chosen as underdogs in this season.
  • This year, St. Louis has won one of seven games when listed as at least +135 or worse on the moneyline.
  • The Cardinals have an implied victory probability of 42.6% according to the moneyline set by sportsbooks for this matchup.
  • The offense for St. Louis is No. 28 in MLB play scoring 3.9 runs per game (225 total runs).
  • Cardinals pitchers have a combined ERA of 4.08 ERA this year, which ranks 18th in MLB.

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Astros Schedule

Date Opponent Score Pitching Matchup
May 30 @ Mariners W 4-0 Spencer Arrighetti vs Logan Gilbert
May 31 Twins L 6-1 Ronel Blanco vs Pablo Lopez
June 1 Twins W 5-2 Framber Valdez vs Joe Ryan
June 2 Twins L 4-3 Hunter Brown vs Simeon Woods Richardson
June 3 Cardinals W 7-4 Justin Verlander vs Kyle Gibson
June 5 Cardinals - Ronel Blanco vs Miles Mikolas
June 7 @ Angels - Framber Valdez vs TBA
June 8 @ Angels - Hunter Brown vs Griffin Canning
June 9 @ Angels - Justin Verlander vs Tyler Anderson
June 10 @ Giants - Spencer Arrighetti vs Kyle Harrison
June 11 @ Giants - TBA vs TBA

Cardinals Schedule

Date Opponent Score Pitching Matchup
May 29 @ Reds W 5-3 Andre Pallante vs Frankie Montás
May 31 @ Phillies L 4-2 Miles Mikolas vs Aaron Nola
June 1 @ Phillies L 6-1 Sonny Gray vs Ranger Suárez
June 2 @ Phillies W 5-4 Lance Lynn vs Taijuan Walker
June 3 @ Astros L 7-4 Kyle Gibson vs Justin Verlander
June 5 @ Astros - Miles Mikolas vs Ronel Blanco
June 6 Rockies - Sonny Gray vs Cal Quantrill
June 7 Rockies - Lance Lynn vs Austin Gomber
June 8 Rockies - Kyle Gibson vs Ryan Feltner
June 9 Rockies - Andre Pallante vs Ty Blach
June 11 Pirates - TBA vs TBA

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dataskrive is a Tribune-Review freelancer. You can contact dataskrive at info@triblive.com.