Saturday's game at Minute Maid Park has the Baltimore Orioles (49-25) squaring off against the Houston Astros (35-40) at 4:10 PM ET (on June 22). Our computer prediction projects a narrow 4-3 victory for the Orioles, so it should be a tight matchup.

The probable pitchers are Corbin Burnes (8-2) for the Orioles and Ronel Blanco (7-2) for the Astros.

Watch MLB, other live sports and more on Fubo! Use our link to sign up for a free trial.

Orioles vs. Astros Game Info & Odds

Place your bets on any MLB matchup at BetMGM, and sign up with our link for a first-time deposit bonus!

Orioles vs. Astros Score Prediction

  • Our pick for this matchup is Orioles 4, Astros 3.

Total Prediction for Orioles vs. Astros

  • Total Prediction: Under 8 runs

Orioles Performance Insights

  • The Orioles have played as the favorite in five of their past 10 games and won four of those contests.
  • Baltimore and its opponents have combined to hit the over four times in its last 10 games with a total.
  • The Orioles have won 37, or 67.3%, of the 55 games they've played as favorites this season.
  • Baltimore has entered 33 games this season favored by -145 or more and is 22-11 in those contests.
  • The implied probability of a win from the Orioles, based on the moneyline, is 59.2%.
  • Baltimore has scored the most runs (390) in baseball so far this year.
  • The Orioles have the second-ranked team ERA among all MLB pitching staffs (3.14).

Astros Performance Insights

  • Over their last 10 games, the Astros have been favored twice and split those games 1-1.
  • In its last 10 games with an over/under, Houston and its opponents have combined to eclipse the total three times.
  • The Astros have been underdogs in 15 games this season and have come away with the win six times (40%) in those contests.
  • Houston has been listed as an underdog of +120 or more on two occasions this season and lost both games.
  • The Astros have an implied victory probability of 45.5% according to the moneyline set by oddsmakers for this matchup.
  • Averaging 4.4 runs per game (328 total), Houston is the 14th-highest scoring team in the majors.
  • Astros pitchers have a combined ERA of 4.12 ERA this year, which ranks 19th in MLB.

Put your picks to the test and bet with BetMGM!

Orioles Schedule

Date Opponent Score Pitching Matchup
June 15 Phillies W 6-2 Grayson Rodriguez vs Taijuan Walker
June 16 Phillies W 8-3 Corbin Burnes vs Zack Wheeler
June 18 @ Yankees L 4-2 Albert Suarez vs Nestor Cortes Jr.
June 19 @ Yankees W 7-6 Cade Povich vs Gerrit Cole
June 20 @ Yankees W 17-5 Cole Irvin vs Luis Gil
June 22 @ Astros - Corbin Burnes vs Ronel Blanco
June 23 @ Astros - Albert Suarez vs Framber Valdez
June 24 Guardians - Cade Povich vs Tanner Bibee
June 25 Guardians - Cole Irvin vs Logan Allen
June 26 Guardians - Grayson Rodriguez vs Carlos Carrasco
June 27 Rangers - Corbin Burnes vs Jon Gray

Astros Schedule

Date Opponent Score Pitching Matchup
June 15 Tigers L 13-5 Spencer Arrighetti vs Jack Flaherty
June 16 Tigers W 4-1 Ronel Blanco vs Kenta Maeda
June 18 @ White Sox L 2-0 Framber Valdez vs Jonathan Cannon
June 19 @ White Sox W 4-1 Hunter Brown vs Garrett Crochet
June 20 @ White Sox W 5-3 Spencer Arrighetti vs Chris Flexen
June 22 Orioles - Ronel Blanco vs Corbin Burnes
June 23 Orioles - Framber Valdez vs Albert Suarez
June 25 Rockies - Hunter Brown vs Austin Gomber
June 26 Rockies - Spencer Arrighetti vs Ryan Feltner
June 28 @ Mets - TBA vs José Quintana
June 29 @ Mets - TBA vs TBA

Rep your team with officially licensed MLB gear! Head to Fanatics to find jerseys, shirts, and much more.

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.

dataskrive is a Tribune-Review freelancer. You can contact dataskrive at info@triblive.com.